Description: Thrombolytic Therapy in Acute Ischemic Stroke by Werner Hacke, Gregory J. DelZoppo, Matthias Hirschberg During the last decade scientists in both basic and clinical research have renew ed their interest in the potential role of thrombolytic therapy in the treatment of acute ischemic stroke. FORMAT Paperback LANGUAGE English CONDITION Brand New Publisher Description The majority of stroke syndromes are caused by thrombotic occlusion of the cerebral arteries. Timely dissolution of blood clots by intravenous or intra-arterial infusion therefore might be a logical treatment strategy for acute thrombotic or embolic stroke. This volume gives an account of the present diagnostic approaches in acute thrombotic and thrombembolic stroke and the rationale for the use of thrombolytic agents in acute stroke. The most dangerous possible side effect of this treatment strategy, haemorrhage, is carefully discussed. Particular attention is paid to the latest developments in thrombolytic drugs. The results of all major safety and efficacy trials on thrombolytic therapy in stroke are also presented. Table of Contents I. Acute Cerebral Ischemia and Thrombolysis.- Natural History of Atherothromboembolic Occlusion of Cerebral Arteries: Carotid Versus Vertebrobasilar Territories.- Fibrinolysis: Thrombolytic Agents, Mechanisms, and New Developments.- Fibrinolysis in Myocardial Infarction: Lessons for Cerebrovascular Disease.- Reperfusion of Ischemic Brain: Why and Why Not!.- Thrombolysis in Stroke: Timing of Recanalization and Its Clinical Consequences.- The Ischemic Penumbra: Fact or Fiction?.- Hemorrhagic Transformation in the Natural History of Acute Embolic Stroke.- Intracranial Hemorrhage After Coronary Thrombolysis with Tissue Plasminogen Activator.- Predictive Factors for the Effective Treatment of Acute Stroke with Intravenous Thrombolytic Agents.- Invasive Imaging Techniques in the Evaluation of Patient Selection and Cerebrovascular Recanalization.- The Role of Noninvasive Imaging Techniques in Cerebrovascular Recanalization.- II. Thrombolysis and Stroke Models.- Thrombolytic Therapy in Ischemic Stroke: Relevance and Limitations of Animal Models.- Update on Animal Model Experience with Recombinant Tissue Plasminogen Activator.- III. Clinical Trials.- Clinical Trials: Some General Considerations.- Intraarterial Urokinase Plasminogen Activator and Streptokinase in Carotid and Vertebrobasilar Territory Stroke: Clinical Outcome.- Fibrinolytic Recanalization Therapy in Acute Cerebrovascular Thromboembolism.- Intravenous Recombinant Tissue Plasminogen Activator in Acute Thrombotic Stroke: Study Design, Recanalization, and Clinical Outcome.- Evaluation of Tissue Plasminogen Activator Early in the Course of Acute Ischemic Stroke.- Intravenous Recombinant Tissue Plasminogen Activator in Acute Stroke.- Thrombolytic Therapy in Embolic and Thrombotic Cerebral Infarction: A Cooperative Study.- IV. Future Directions.- Problems in Formulating Therapeutic Trials.- Invasive and Noninvasive Vascular Imaging Techniques and Their Role in Clinical Stroke Trials.- Strategies for Early Treatment of Acute Cerebral Infarction.- V. Open Communications.- Topical Intraarterial Urokinase Infusion for Acute Stroke.- Local Thrombolytic Therapy in Acute Basilar Artery Occlusion: Experience with 18 Patients.- Vertebrobasilar Occlusion: Outcome With and Without Local Intraarterial Fibrinolysis.- Recanalization of Acute Middle Cerebral Artery Occlusion Monitored by Transcranial Doppler Sonography.- Neuropathological Findings After Thrombolytic Therapy in Acute Ischemic Stroke.- How Many Stroke Patients Are Candidates for Thrombolysis?.- Spontaneous Recanalization in Middle Cerebral Artery Occlusion.- In Vitro Thrombus Lysis by Urokinase in Preparation for Patient Studies.- Local Intraarterial Fibrinolysis in Acute Middle Cerebral Artery Occlusion.- Treatment of Acute Ischemic Stroke with Recombinant Tissue Plasminogen Activator: Evaluation with Regional Cerebral Blood Flow Single Photon Emission Computed Tomography.- Thrombolytic Therapy in Acute Ischemic Stroke: The Copenhagen Multicenter Study.- Thrombolytic Therapy in Cerebral Sinus Thrombosis: A Case Report.- Basilar Artery Occlusion Associated with Protein C Deficiency: Successful Treatment Using Recombinant Tissue Plasminogen Activator Infusion.- Intracerebral Hemorrhage and Infarction Volume Following Recombinant Tissue Plasminogen Activator in an Acute Stroke Model.- Prourokinase Therapy in Stroke. Promotional Springer Book Archives Long Description During the last decade scientists in both basic and clinical research have renew Details ISBN3540536809 Publisher Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Year 1991 ISBN-10 3540536809 ISBN-13 9783540536802 Format Paperback Imprint Springer-Verlag Berlin and Heidelberg GmbH & Co. K Place of Publication Berlin Country of Publication Germany DEWEY 616.81061 Short Title THROMBOLYTIC THERAPY IN ACUTE Language English Media Book Publication Date 1991-06-11 Subtitle Symposium Entitled "Thrombolysis in Acute Cerebral Ischemia" : Papers Pages 271 Edition 1991st DOI 10.1007/978-3-642-76439-4 Edited by Matthias Hirschberg Author Matthias Hirschberg Edition Description 1991 ed. Audience Postgraduate, Research & Scholarly Illustrations 26 Illustrations, black and white; XII, 271 p. 26 illus. We've got this At The Nile, if you're looking for it, we've got it. 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ISBN-13: 9783540536802
Book Title: Thrombolytic Therapy in Acute Ischemic Stroke
Number of Pages: 271 Pages
Language: English
Publication Name: Thrombolytic Therapy in Acute Ischemic Stroke
Publisher: Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg
Publication Year: 1991
Subject: Medicine, Radiology
Item Height: 235 mm
Item Weight: 450 g
Type: Textbook
Author: Matthias Hirschberg, Werner Hacke, Gregory J. Delzoppo
Item Width: 155 mm
Format: Paperback
