Description: Keeps hair in the growth phase longerIncreases number of hairs in the scalpReduces shedding after 6 daysIncreases growth factors that make hair growActivates Wnt-signalling pathway -- the key to hair growthIncreases scalp IGF-1Reduces scalp TGFs, preventing hair lossEnables hair to grow longer, stronger and thickerIncreases hair density Breakthrough 1: Valproic acidActivates the Wnt-signalling pathway, enabling hair follicle neogenesisValproic acid (VPA) is perhaps the most important ingredient for the creation of brand new hair follicles via the process of wound-induced hair follicle neogenesis.VPA induced ALP in human dermal papilla cells by up-regulating the Wnt/β-catenin pathway, whereas minoxidil (MNX), a drug commonly used to treat alopecia, did not significantly affect the Wnt/β-catenin pathway. VPA analogs and other GSK3β inhibitors that activate the Wnt/β-catenin pathway such as 4-phenyl butyric acid, LiCl, and BeCl2 also exhibited hair growth-promoting activities in vivo. Importantly, VPA, but not MNX, successfully stimulate hair growth in the woundsVia Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, South KoreaBreakthrough 2: SandaloreIncreases growth factor IGF-1, reduces TGFs and lengthens hair growth (anagen) phaseSandalore has hit major news headlines in the United Kingdom and has been hailed as the miracle cure for hair loss. And yet very few people know about it.We have sourced our Sandalore in pure form directly from the original manufacturer here in the United Kingdom. This is the only Sandalore that stimulates hair growth. Sandalore is a remarkable ingredient, due to the significant effect on hair growth in tests. The chemical interacts with an olfactory receptor in the scalp causing an increase in IGF-1 and lengthening of the hair (anagen) growth phase, meaning hair grows for a longer period of time, reducing hair loss.Results proved promising, concluding that Sandalore targeted the expressed olfactory receptor, OR2AT4. This leads to a reduction in keratinocyte apoptosis and a 25% increase in IGF-1, so prolonging the anagen phase. There was also a corresponding 25% decrease in TGF-2, another protein regulator of the hair growth cycle, but one which progresses hair loss.Castor oilIncreases PGE2 and works as a natural carrier oilCastor oil contains a high concentration of ricinoleic acid. This is the key to its effectiveness. Ricinoleic acid increases PGE2 in the scalp. PGE2 is a fatty acid, which seems to be vital for hair growth. Castor oil is also useful for naturally thickening the serum, which makes application using the Hair Follicle Neogenesis Method very easy to do from home without any need for assistance or medical equipment.CysteineShown in multiple independent studies to significantly increase hair growthIn a paper regarding evidence-based guidelines in the treatment of alopecia for both women and men (Blumeyer et al.), various amino acids are mentioned with a special mention for cysteine. Cysteine is considered to be one of the main factors involved in hair growth.The paper cites a study (Morganti et al.) where there was a significant mean change of total hair count in both male and female patients after a treatment containing cysteine.L-Carnitine L-TartrateUpregulates proliferation of follicular keratinocytesTopical carnitine has been shown to significantly increase hair count by upregulating proliferation of follicular keratinocytes. And it even works for male pattern hair loss.CaffeineShown in studies to reduce DHT and increase hair growthThe proposed mechanism which would counteract DHT-induced miniaturization of the hair follicle include inhibition of phosphodiesterase by caffeine, which increases cAMP levels in cells and therefore promotes proliferation by stimulating cell metabolism.[5] A study conducted by Fischer et al. used hair organ culture model to investigate the effects of testosterone and caffeine on hair follicle growth stimulation. This in vitro study used scalp biopsy samples from male AGA patients which were cultivated using different concentrations of testosterone and/or caffeine for a period of 120-192 hours. Addition of caffeine in concentrations of 0.001% and 0.005% were found to counteract the suppressive effects of testosterone on hair growth, with a higher hair shaft elongation seen at 120 h after caffeine administrationThe International Journal of TrichologyPeppermint oilReduces inflammation and increases IGF-1Peppermint oil is a natural plant extract, which has been shown in studies to have powerful anti-hair-loss properties. As I said in my article about peppermint oil, I am truly amazed at the results of one study that tested peppermint oil on hair loss patients:(PEO: peppermint oil. SA: saline solution. JO: Jojoba oil. MXD: Minoxidil.)From week 2, PEO grew hair more rapidly than SA and JO. At week 3, PEO remarkably promoted hair growth than SA and JO, even greater than MXD. At week 4, PEO showed hair growth about 92%, whereas MXD about 55%NCBIVelvet deer antlerincreases growth factor IGF-1 enabling hair follicle neogensisIn a study of wound-induced hair follicle neogenesis, velvet deer antler was applied to wounds and hair counts were taken on days 16, 32 and 40. The researchers revealed that “longer and more active new hair appeared around the healing wound of antler-treated skin”.CetirizineEffectively reduces PGD2, preventing hair follicle deathCetirizine is an anti-histamine. This is a key ingredient in the mixture because it reduces PGD2 when applied to the scalp. In one experiment, 1% cetirizine was applied to the scalps of subjects and ‘significant hair growth’ was reported. Almost all hair loss is related to elevated PGD2 (which is related to auto-immune reactions in the skin). It’s critical to reduce PGD2 in order to prevent hair loss.TaurineReduces TGFs, reduces fibrosis and stimulates hair growthAnother study conducted in 2008 (Collin et al.) analysed taurine in relation to transforming growth factors that cause hair follicles to stop growing. Taurine is involved in many physiological functions among which the immunomodulatory and antifibrotic functions. The researchers used taurine on in-vitro hair follicles. The observations concluded that taurine protects the hair follicle from the effects of TGFs1, promoting hair survival.
Price: 39.99 GBP
Location: Maidenhead
End Time: 2023-12-26T13:55:02.000Z
Shipping Cost: 12.65 GBP
Product Images
Item Specifics
Return postage will be paid by: Buyer
Returns Accepted: Returns Accepted
After receiving the item, your buyer should cancel the purchase within: 30 days
Size: 50ml
Country/Region of Manufacture: United Kingdom
Department: Unisex
Custom Bundle: No
Formulation: Serum
Period After Opening (PAO): 12M
Hair Type: All Hair Types, Damaged Hair, Dry Hair, Fine Hair, Thin Hair
Type: Growth Promoter
Features: Increases growth factors that make hair grow, Activate Wnt-signalling pathway, Increases scalp IGF-1, Reduces scalp TGFs, preventing hair loss, Prolongs the hair's growth phase, Ammonia-Free, Contains Minerals, Contains Vitamins, Cruelty-Free/No Animal Testing, Dye-Free
Action 4: Increase VEGF
Action 8: Prevent hair loss
Action 5: Increase IGF-1
Action 9: Reduce hair loss
Volume: 50ml
Ingredient: Valproic acid
Action 2: Growth factors
Action 6: Increase hair density
Brand: Hair Follicle Neogenesis
Action 3: Increase scalp blood circulation
Gender: Unisex
Action: Hair growth stimulator
Action 7: Make hair thicker
Dosage: 10%
