Description: Homing Endonucleases : Methods and Protocols, Hardcover by Edgell, David R. (EDT), ISBN 1627039678, ISBN-13 9781627039673, Brand New, Free shipping in the US
Homing Endonucleases: Methods and Protocols aims at providing molecular biologists with a comprehensive resource to identify and characterize homing endonucleases from genomic sequence, to deduce the biological basis of binding and cleavage specificity, as well as to provide protocols to redesign endonuclease target specificity for genome-editing applications. Engineering of designer homing endonucleases has set the stage for genome editing of complex eukaryotic genomes with a broad range of potential applications including targeted gene knockouts in model organisms and gene therapy in humans, making this book a valuable resource for future research.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Homing Endonucleases: Methods and Protocols serves as a key reference for all labs studying site-specific DNA endonucleases.
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Book Title: Homing Endonucleases : Methods and Protocols
Number of Pages: X, 284 Pages
Language: English
Publication Name: Homing Endonucleases : Methods and Protocols
Publisher: Humana Press
Subject: Genetics, Chemical & Biochemical, Chemistry / Industrial & Technical, Chemistry / Organic
Publication Year: 2014
Item Weight: 271.3 Oz
Type: Textbook
Item Length: 10 in
Author: David R. Edgell
Subject Area: Technology & Engineering, Science, Medical
Series: Methods in Molecular Biology Ser.
Item Width: 7 in
Format: Hardcover