Excitatory-Inhibitory Balance: Synapses, Circuits, Systems by Takao K. Hensch (E

Description: Excitatory-Inhibitory Balance by Takao K. Hensch, Michela Fagiolini Moreover, this book this book features active young researchers from around the world, who are currently educating the brain scientists of tomorrow. FORMAT Paperback LANGUAGE English CONDITION Brand New Publisher Description A new perspective on brain function depends upon an understanding of the interaction and integration of excitation and inhibition. A recent surge in research activity focused on inhibitory interneurons now makes a more balanced view possible. Technological advances such as improved imaging methods, visualized patch-clamp recording, multiplex single-cell PCR, and gene-targeted deletion or knock-in mice are some of the novel tools featured in this book. This book will provide an integrated view of neuron function, operating in a balanced regime of excitation and inhibition. It is a timely contribution emphasizing how this balance is established, maintained, and modified from the molecular to system levels. The broad spectrum of topics from molecular to cellular and system/computational neuroscience will appeal to a wide audience of advanced graduate students, post-docs, and faculty. Moreover, this book this book features active young researchers from around the world, who are currently educating the brain scientists of tomorrow. Table of Contents Historical Overview: Search for inhibitory neurons and their function.- I. Synapses.- 1. The organization and integrative function of the post-synaptic proteome.- 2. Dynamism of postsynaptic proteins as the mechanism of synaptic plasticity.- 3. Construction, stability and dynamics of the inhibitory postsynaptic membrane.- 4. Long-term modification at visual cortical inhibitory synapses.- 5. Activity-dependent modification of cation-chloride co-transporters underlying plasticity of GABAergic transmission.- 6. Endocannabinoid-mediated modulation of excitatory and inhibitory synaptic transmission.- II. Circuits.- 7. Balanced recurrent excitation and inhibition in local cortical networks.- 8. Local circuit neurons in the frontal cortico-striatal system.- 9. Interneuron heterogeneity in neocortex.- 10. Fast spiking cells and the balance of excitation and inhibition in the neocortex.- 11. Homeostatic regulation of excitatory-inhibitory balance.- 12. Adult neurogenesis controls excitatory-inhibitory balance in the olfactory bulb.- III. Systems.- 13. GABAA receptor subtypes: memory function and neurological disorders.- 14. LTD, spike timing and somatosensory barrel cortex plasticity.- 15. Maintaining stability and promoting plasticity: context-dependent functions of inhibition.- 16. Spike timing and visual cortical plasticity.- 17. Excitatory-inhibitory balance controls critical period plasticity. Promotional Springer Book Archives Long Description A new perspective on brain function depends upon an understanding of the interaction and integration of excitation and inhibition. A recent surge in research activity focused on inhibitory interneurons now makes a more balanced view possible. Technological advances such as improved imaging methods, visualized patch-clamp recording, multiplex single-cell PCR, and gene-targeted deletion or knock-in mice are some of the novel tools featured in this book. This book will provide an integrated view of neuron function, operating in a balanced regime of excitation and inhibition. It is a timely contribution emphasizing how this balance is established, maintained, and modified from the molecular to system levels. The broad spectrum of topics from molecular to cellular and system/computational neuroscience will appeal to a wide audience of advanced graduate students, post-docs, and faculty. Moreover, this book this book features active young researchers from around the world, who are currently educating the brain scientists of tomorrow. Details ISBN1461348951 Language English Subtitle Synapses, Circuits, Systems Edition 03200th ISBN-10 1461348951 ISBN-13 9781461348955 Short Title EXCITATORY-INHIBITORY BALANCE Media Book DEWEY 612.8 Year 2012 Publication Date 2012-09-17 Imprint Springer-Verlag New York Inc. Place of Publication New York, NY Country of Publication United States Edited by Michela Fagiolini UK Release Date 2012-09-17 AU Release Date 2012-09-17 NZ Release Date 2012-09-17 US Release Date 2012-09-17 Author Michela Fagiolini Illustrations X, 288 p. Pages 288 Publisher Springer-Verlag New York Inc. Edition Description Softcover reprint of the original 1st ed. 2004 Format Paperback Alternative 9780306479625 Audience Professional & Vocational We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:96351314;

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