B Cell Receptor Signaling by Tomohiro Kurosaki (English) Hardcover Book

Description: B Cell Receptor Signaling by Tomohiro Kurosaki, JÜrgen Wienands Estimated delivery 3-12 business days Format Hardcover Condition Brand New Description Altogether, the discoveriespresented provide a better understanding of B cell biology and help to explainsome B cell-mediated pathogenicities, like autoimmune phenomena or theformation of B cell tumors, whilealso paving the way for eventually combating thesediseases. Publisher Description Thisvolume details our current understanding of the architecture and signalingcapabilities of the B cell antigen receptor (BCR) in health and disease. Thefirst chapters review new insights into the assembly of BCR components andtheir organization on the cell surface. Subsequent contributions focus on themolecular interactions that connect the BCR with major intracellular signalingpathways such as Ca2+ mobilization, membrane phospholipidmetabolism, nuclear translocation of NF-kB orthe activation of Brutons Tyrosine Kinase and MAP kinases. These elementsorchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamicsfor antigen internalization. Furthermore, a key mechanism of how B cellsremember their cognate antigen is discussed in detail. Altogether, the discoveriespresented provide a better understanding of B cell biology and help to explainsome B cell-mediated pathogenicities, like autoimmune phenomena or theformation of B cell tumors, whilealso paving the way for eventually combating thesediseases. Author Biography Tomohiro Kurosaki, MD, PhD, is a professor at WPI Immunology Frontier Research Center at Osaka University, JapanJÜrgen Wienands, PhD, is a professor of Cellular and Molecular Immunology at the University of Göttingen, Germany Details ISBN 3319261312 ISBN-13 9783319261317 Title B Cell Receptor Signaling Author Tomohiro Kurosaki, JÜrgen Wienands Format Hardcover Year 2016 Pages 231 Edition 1st Publisher Springer International Publishing AG GE_Item_ID:137567393; About Us Grand Eagle Retail is the ideal place for all your shopping needs! With fast shipping, low prices, friendly service and over 1,000,000 in stock items - you're bound to find what you want, at a price you'll love! Shipping & Delivery Times Shipping is FREE to any address in USA. Please view eBay estimated delivery times at the top of the listing. Deliveries are made by either USPS or Courier. We are unable to deliver faster than stated. International deliveries will take 1-6 weeks. NOTE: We are unable to offer combined shipping for multiple items purchased. This is because our items are shipped from different locations. Returns If you wish to return an item, please consult our Returns Policy as below: Please contact Customer Services and request "Return Authorisation" before you send your item back to us. Unauthorised returns will not be accepted. Returns must be postmarked within 4 business days of authorisation and must be in resellable condition. Returns are shipped at the customer's risk. We cannot take responsibility for items which are lost or damaged in transit. For purchases where a shipping charge was paid, there will be no refund of the original shipping charge. Additional Questions If you have any questions please feel free to Contact Us. Categories Baby Books Electronics Fashion Games Health & Beauty Home, Garden & Pets Movies Music Sports & Outdoors Toys

Price: 223.57 USD

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End Time: 2024-12-27T03:32:44.000Z

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